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Lab Coordinator- Immunobiology and Microbial Pathogenesis, Dr. Hollern

Salk Institute for Biological Studies La Jolla, CA

  • Posted: over a month ago
  • Full-Time
  • Benefits: 401k, dental, life insurance, medical, vision
Job Description: ABOUT THE POSITION The Hollern Lab is seeking an individual who is passionate about science, cancer research, and helping people, is organized, and is comfortable executing protocols at the bench for the position of Lab Coordinator at the Salk Institute for Biological Studies in La Jolla (San Diego) California. The main focus of the Hollern lab is to understand the immunological and molecular landscape of tumors with the goal of leveraging the immune component to promote anti-tumor responses. In more detail, the lab is particularly interested in developing these approaches through the study of B cells and T cells. These studies will be pursued in mouse models and patient specimens. The lab utilizes a multidisciplinary approach blending biologically appropriate models, molecular biology, and genomic analytical techniques including single cell and spatial transcriptomics and proteomics to interrogate pertinent questions in a number of in vitro and in vivo translational studies of breast cancer. Position Highlights:Be involved in exciting projects to understand the immunobiology of solid cancers.Serve as a lab leader and support a team of innovative scientists.Explore novel immunotherapeutic strategies.Conduct collaborative studies in an Immunology lab focusing on clinically-relevant translational studies.Collaborate with investigators across the globe.Opportunity to learn techniques in single-cell and spatial computational genomics and immuno-oncology by projects investigating beneficial patient outcomes and anti-tumor immunity.Opportunity to develop new models for immune-oncology research.Work toward and contribute to manuscripts. SUMMARY OF DUTIES The Lab Coordinator is responsible for overall lab management duties in support of the assigned Principal Investigator’s (PI) and their laboratories. Supervises and performs technical and administrative tasks. Demonstrates proficiency to operate and teach essential lab protocols. Must be open to training to keep pace with advances in technology and the lab. Maintains adequate inventory of materials and equipment to ensure adequate supplies for experimental needs. Responsible for pre-award and post-award services for the PI and research staff. Assists in the development of grant materials and budgets. Maintains familiarity with federal and state grant rules and processes. Manages lab safety programs to ensure compliance with all applicable regulations. Assists Investigator in personnel management. Conducts scientific research (bench work and computational), scientific project management, and data analysis as needed. ESSENTIAL FUNCTIONS (40%) Research Support:Instructs and guides laboratory staff on lab protocols and techniques, to include entry-level staff and Postdoctoral FellowsPerforms molecular biology techniques (library prep protocols, plasmid assembly, cloning, flow cytometry)Performs tissue culture techniquesPerforms bioinformatics analysis (training available)Managing murine coloniesIndependently formulates, analyzes, recommends, and executes protocols (40%) Laboratory Administrative ManagementManage entry-level lab staff to include Lab Technicians, Students, and/or Volunteers, this includes oversight of employment and assignment activities, performance expectations, and work product for applicable personnel.Manage day-to-day operational activities within the research laboratory, including but not limited to ensuring operation of essential equipment, making sure adequate supplies are available for routine experimental procedures, reviewing budgets, etc.Assist PI with preparation of materials, data, and information required for grants, meetings, conferences and other scheduled events. Oversee and participate in the distribution of communications and information to the lab group members.As delegated, serves as the primary liaison to partnering labs or departments on a variety of operational matters. In coordination with and with final approval from the PI when necessary, is given latitude to make many operational decisions on behalf of the lab.Compose correspondence on subject matters that require considerable sensitivity, discretion, judgment, or negotiation in replying to inquiries, and/or presenting or requesting information.Use spreadsheet and database software to develop and maintain a variety of databases.Determine needs and purchase office supplies and equipment; facilitate office equipment maintenance. (20%) Research Funds Management and Grant SupportManage and maintain financial expenses and reporting.Calibrate the financials with Finance and Accounting on a quarterly basis; coordinates with Finance and Accounting on a regular basis. Research details to explain deviations in reports.Manage, compile and submit grant proposals. EXPERIENCE Required:4 or more years of related experience, which may include experience as a Graduate Student, Postdoctoral Fellow, Research Assistant/Technician or relatedExperienced in successfully interacting with a variety of people, including academics, staff, high-level executives, and members of the community from diverse cultures and backgrounds.Experience in a lead capacity to include providing work direction and guidance to others Preferred:5 or more years of related experience focused in laboratory management EDUCATION RequiredBachelor’s degree in biological sciences, life sciences or related field or equivalent. PreferredPhD or Master’s degree in biological sciences, life sciences or related field. SKILLS AND ABILITIES RequiredTheoretical knowledge of biological sciences;Demonstrated ability to conduct and oversee independent research. This includes the ability to (a) develop, maintain, execute, and complete research projects of varying size and scope; (b) critically read, understand, and extract information from published medical, chemical, and biological literature to prepare background information for scientific abstracts, manuscripts, lectures, and grant proposals; (c) perform basic data and statistical analysis; and (d) produce high-quality abstracts, manuscripts, lectures, and grant applications.Ability to independently design experiments and debug protocols.Ability and interest in learning new scientific techniques.Ability to manage and track large numbers of samples meticulously without mix-up or cross contamination.Demonstrated ability to prioritize and work independently.Demonstrated knowledge and experience with both PC and MAC operating systems, standard business office equipment and commonly used software and tools, such as Microsoft Office, electronic mail, and the internet.Strong interpersonal skills. Ability to establish and maintain effective working relationships; interact with all levels of management and employees across multiple departments. Ability to communicate and act as a liaison with a diverse audience of professionals. Demonstrated ability to supervise and train students and other technicians.Knowledge of standard laboratory management and safety procedures.Ability to analyze and interpret data and assist with writing scientific papers and grants.Ability to review the scientific literature and apply to experimental designAbility to make independent decisions, analyze situations, solve problems, and initiate actions for the effective management of a large and complex department.Strong analytical and critical thinking skills to identify problems and develop innovative solutions.Excellent written skills and knowledge of English language, including grammar, usage, spelling, and punctuation.Excellent oral communication skills. Demonstrated ability to communicate clearly, effectively, tactfully, and patiently in person, on the telephone, and in writing to a diverse group of people (including researchers, health care providers, patients, research participants, administrators, industry representatives) in the academic, scientific, medical, and commercial communities. Preferred:R programming skills.UNIX programming skills. SPECIAL CONDITIONS OF EMPLOYMENTMust be willing to work in an animal-related research environment.Must be willing to work an adjusted schedule to support research needs.Must be willing to learn new techniques.Successful completion of the Institute’s background investigation.Must be willing to sign an employee confidentiality agreement. PHSYCIAL REQUIREMENTS This position requires constant standing, analyzing, communicating, reasoning and working inside. Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information. 41 CFR 60-1.35(c) Company Description: The Salk Institute for Biological Studies is one of the world's preeminent basic research institutions, where internationally renowned faculty probe fundamental life science questions in a unique, collaborative, and creative environment. Focused on both discovery and mentoring future generations of researchers, Salk scientists make groundbreaking contributions to our understanding of cancer, aging, Alzheimer's, diabetes, and cardiovascular disorders by studying neuroscience, genetics, cell and plant biology, and related disciplines. Faculty achievements have been recognized with numerous honors, including Nobel Prizes and memberships

Salk Institute for Biological Studies

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Salk-Where Cures Begin. We explore the very foundations of life for the benefit of all.

The Salk Institute for Biological Studies is one of the world's preeminent basic research institutions, where internationally renowned faculty probe fundamental life science questions in a unique, collaborative, and creative environment. Focused on both discovery and mentoring future generations of researchers, Salk scientists make groundbreaking contributions to our understanding of cancer, aging, Alzheimer's, diabetes, and cardiovascular disorders by studying neuroscience, genetics, cell and plant biology, and related disciplines. Faculty achievements have been recognized with numerous honors, including Nobel Prizes and memberships in the National Academy of Sciences. Founded in 1960 by polio vaccine pioneer Jonas Salk, M.D., the Institute is an independent nonprofit organization and architectural landmark. Salk Equal Opportunity and Non-Discrimination Statement The Salk Institute for Biological Studies is committed to providing equal access to opportunities for students, employees, applicants for employment and other persons. Our policies prohibit harassment or unlawful discrimination against individuals on the basis of sex, gender, marital or parental status, pregnancy, childbirth, breastfeeding, medical conditions/disabilities related to pregnancy, childbirth or breastfeeding, gender identity, gender expression, or sexual orientation age, ancestry, color, religion (including religious dress and grooming practices), family and/or medical care leave status, disability (mental or physical), registered domestic partner status, legally protected medical condition, genetic information, military or veteran status (disabled veteran, veteran of the Vietnam era, other covered veteran status), national origin (including language use restrictions and possession of a driver’s license), race, religion or any other classification protected by local, state or federal laws. The Salk Institute participates in the E-Verify program. Reasonable accommodation is available for qualified individuals with disabilities and for individuals with religious restrictions.

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