The Duke Brain Tumor Immunotherapy Program (BTIP) has a singular, all-encompassing goal: develop novel, safe, and effective immune-based therapies for patients with brain tumors. Our research projects are spearheaded by an outstanding complement of graduate students, medical students, residents, postdoctoral fellows, and junior and senior scientists assembled under the umbrella of the Duke BTIP. The Duke BTIP combines the necessary funding support, intellectual and physical resources, and visionary leadership to meet its devoted objective of “pioneering translational immunotherapy” for the treatment of patients with malignant brain tumors. As a result, our program has offered brought more immunotherapies to trial for these patients than almost entity in the world. We are currently looking for a Research Analyst to join our team. The responsibilities will include: Coordination of the manufacture of cGMP of autologous cellular products for 7 IND sponsored trials. Coordinate vaccine creation and application of vaccine with study coordinators and service providers of the Duke Brain Tumor Center. Communicate with outside vendors as needed. Collect raw material (patient blood cells) from clinic. Orders all supplies for the cGMP manufacture of autologous products utilizing Duke financial systems. Writing new Standard Operating Procedures (SOP) and Batch Records (BR). Participate in drug product release testing, including but not limited to endotoxin, gram stain, QPCR for integrated gene copy number and replication component retrovirus. Developing a new procedure for the elutriation of monocytes. Involved in writing Out of Specification, Corrective and Preventative Actions and process Deviations. Maintain the clean rooms and all equipment used in the manufacture of GMP cellular products. Knowledge of sterilization techniques important. This position may be physically demanding at times. It may require long-term standing. The candidate for the position should expect excessive walking between buildings.
Strongly Preferred Qualifications: 1 to 3 years of lab experience. Experience with tissue culture and experience handling human cells and blood products. GMP experience. Experience writing SOP’s helpful. Knowledgeable of MS Office (Powerpoint, Word, Excel, Outlook). Experience with Master Control helpful.