Medical Director

CARGO is hiring a Medical Director to help support the advancement of our early and late phase cell therapy programs. This leader will partner closely with the Clinical Leadership Team and study teams to identify, influence and support priority initiatives and contribute to a high functioning leadership team and organization. This leader reports to the VP, Head of Clinical Development and will include active engagement with the CMO. We are seeking a highly motivated individual who possesses a technical understanding of clinical development and can manage multiple cross-functional development activities.

The successful candidate will work closely with the clinical, regulatory, clinical operations, biomarker, biometrics functions, and the broader team to support strategy and associated timelines for CARGO cell therapy products. The individual will also collaborate cross-functionally to ensure timely development and support regulatory submissions.

The role is based in San Mateo, CA, but may also be suitable for a hybrid arrangement.

WHAT YOU’LL DO AT CARGO THERAPEUTICS 

• Design and optimize clinical trials, including development of clinical protocols and amendments, Investigator Brochures (IB), safety management guidelines, etc.
• Act as Clinical lead on the direction, planning, execution, and interpretation of clinical trials and data collection activities; includes leading interactions with study investigators
• Serve as medical monitor, including evaluation of the safety, pharmacology, and efficacy in ongoing and completed studies in close collaboration with the Clinical Operations team
• Work with Safety Science on safety signal detection efforts, adverse event reporting, and safety monitoring
• Align with the Development team on clinical development plans that integrate pre-clinical and early clinical findings while working to ensure cross-functional alignment on an ongoing basis throughout the phases of clinical development
• Collaborate with translational science on developing relevant scientific research questions within the clinical studies, including interpretation of the literature and impact on programs
• Serve as key author for clinical sections on reports and responses submitted to the FDA, EMA, and other relevant health authorities, as well as abstracts, manuscripts, and clinical study reports in collaboration with the Clinical Development team members
• Provide key medical expertise and input in supporting the development of early stage pipeline assets
• Travel – Domestic and International, approximately 20-25%

THE RIGHT STUFF: Required Experience & Qualifications 

• MD or equivalent degree; board certified in Oncology or Hematology
• 3-5 years of industry experience relevant to drug development that includes designing, leading, and managing clinical studies
• Experience in CAR T-cell therapy or bone marrow transplant is desired, but not required
• Expertise in drug trial design, scientific writing, and the successful implementation of clinical protocols and clinical study reports
• Ability to show function independently in the design, execution, and analysis of study data with light-touch supervision 
• Knowledge of GCP, FDA/EMA regulations, and other applicable regulatory requirements
• Experience working effectively in a fast-paced, team-based environment; able to multitask and be a self-starter
• Excellent time management and organizational skills, with the ability to adapt to a changing work environment with proven agility in prioritizing and navigating competing demands
• Strong communication skills in relating scientific/technical concepts and strategies effectively to multi-disciplinary teams, including scientists, principal investigators, and non-scientific staff
• Strong technical writing, oral, and interpersonal communication skills

PAY RANGE

The combined pay range for this role is from $270,000 - $300,000. Title and salary will be based on our assessment of skills and experience relevant to our needs for the role.

ABOUT CARGO THERAPEUTICS 

CARGO Therapeutics is engineering best-in-class CAR T-cell therapy to overcome resistance to cancer treatment and address barriers to access so that more patients may benefit from potentially curative therapies. CARGO is on a mission to outsmart cancer by advancing a new generation of best-in-class chimeric antigen receptor (CAR) T-cell therapies. Despite advances made by commercially available autologous CARs, these treatments are curative for fewer than half of all cancer patients. In addition, far too many patients are unable to access these potentially curative therapies due to other challenges, including manufacturing, supply constraints, slow turnaround time and reimbursement hurdles. The team at CARGO is intensely focused on pursuing novel solutions to achieve better cancer treatment outcomes and experiences.  

Our founders are pioneers and world experts in CAR T cell therapy, and we have built a team with experience and success developing, manufacturing, launching and commercializing oncology and cell therapy products. CARGO Therapeutics colleagues share a passion to help others thrive. We are tenacious in the relentless pursuit of our mission, and we innovate to change the game for the patients we serve. 

Join us to help make a difference! 

EEO & EMPLOYMENT ELIGIBILITY  

CARGO Therapeutics, Inc. is committed to building a diverse, equitable, and inclusive company. We provide equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability, or veteran status. CARGO Therapeutics, Inc. also complies with all applicable national, state, and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification required of applicable law. 

CARGO Therapeutics requires all new hires to be fully vaccinated against COVID-19 as of their start date.  This requirement is a condition of employment at CARGO Therapeutics, and it applies regardless of whether the position is located at a CARGO Therapeutics site or is fully remote.  If you are unable to receive the vaccine due to a disability or serious medical condition, or because it is prohibited because of your sincerely held religious beliefs, you will have an opportunity to request a reasonable accommodation.