Sr. Research Associate - CRISPR Screening

Research Associate II/SR Research Associate - CRISPR Screening

Direct Hire Fulltime Role

Salary Range: $90,000 - $110,000 per year

Location: South San Francisco, CA - Onsite Role

Job Description:

We are now looking for curious, passionate, and motivated scientists to join an organization developing the next generation of genomic medicines.

What you will accomplish here:

• Develop high-throughput functional screening platforms for a portfolio of cell therapy applications
• Develop DNA constructs and cellular CRISPR libraries
• Develop, evaluate, optimize, and implement new technologies, laboratory protocols, and methodologies for biochemical and cell-based assays
• Provide expert support for multiplexing and scaling biological readouts across our broader scientific team
• Maintain familiarity with the relevant current literature and its application to multiplexing readouts and cell therapy
• Coordinate tasks across multiple projects, demonstrating prioritization and planning
• Interpret and effectively execute experiments in line with project timelines and goals

Qualifications:

• BS/MS in molecular biology, cell biology, biotechnology, pharmaceutical or related fields, with 3+ years of relevant research experience in industry or academia
• Strong knowledge of sterile technique with significant experience maintaining cell lines and primary cell cultures
• Ability to quickly learn new skills and knowledge on the job, demonstrate productivity, and deliver high-quality results

Strong candidates will also possess the following skills:

• Lentivirus packaging and transduction
• DNA and RNA extraction/purification (mini and maxi preps, etc.)
• PCR/RT-PCR
• Molecular cloning (digestion, ligation, gel electrophoresis, etc.)
• Experience using CRISPR technologies for cell line engineering (knockout, knock-in, base-editing, CRISPRi/a)
• Flow cytometry
• Working knowledge of NGS technologies and workflows

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