Research Associate II, Technology

(Job 2023BR-08)

About Ambrx:

Ambrx (NASDAQ: AMAM) is a clinical-stage biologics company focused on discovering and developing a novel class of specific and selective engineered precision biologics, using our proprietary platform technology that allows site-specific incorporation of synthetic amino acids (SAAs) into proteins within living cells. Our product candidates are designed to overcome the inherent limitations of conventional conjugation approaches that use non-site-specific conjugation, in order to optimize for safety and efficacy benefits across multiple therapeutic classes in broad therapeutic areas.

Ambrx is seeking a highly motivated Research Associate to join the Discovery Group. The primary responsibility is to support multiple oncology and immune-oncology projects from discovery to the preclinical phase. The candidate will work in a multidisciplinary and dynamic team environment to help with discovery and develop precision engineered biological drugs that change patients’ lives.

Major Responsibilities:

• Work in the Discovery Group to support multiple discovery projects to expand Ambrx’s early pipeline
• Build DNA constructs for various formats of biological therapeutics
• Collaborate seamlessly with cell culture group to quickly deliver protein material for discovery projects
• Generate recombinant stable cell lines for assay development and preclinical animal models
• Develop and perform in vitro biological assays to characterize drug candidates

Job Requirements:

• MS degree with 0-4 years of experience, or BS degree with 2-4 years of experience, in the biotech and /or pharmaceutical industry
• Prior experience or good knowledge in molecular biology, especially in cloning, PCR, and vector construction
• Prior experience or good knowledge in recombinant protein expression in a wide variety of systems (bacterial, mammalian cells)
• Prior experience in aseptic tissue culture, in vitro biological assays, ELISA desirable
• Prior experience working with oncology and immune-oncology therapeutic proteins and translational science is a plus
• Demonstrated passion to learn and advance new technology
• Ability to work independently and collaboratively in a matrixed team environment
• Good oral/ written communication and strong problem-solving skills

Pay Scale:

The pay scale for this position is annualized at: $ 65,000 to $ 80,000, commensurate with experience. We believe this to be possible compensation for this role at the time of this posting, and we may modify this pay scale in the future.

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