The High Throughput Automation scientist will ensure that current and future automation is appropriately used to deliver value to GSK projects. Accordingly this person will implement innovative automated platforms and workflows in collaboration with various US-based scientific functions. As such, the purpose of the role is to:
• Successfully utilize the automation assets for rapid screening and development in order to reduce design selection risks and enhance product design across all phases of pharmaceutical development.
• Develop appropriate automation protocols to meet the needs of the analysts, chemists, engineers and formulation scientists.
• Conduct high throughput automated experiments, exploring both the physical properties of materials, excipients of pharmaceutical relevance and chemical reactions of synthetic intermediates.
• Write protocols for new automation workflows primarily using Unchained Labs LEA Library Studio and Automation Studio.
• Participate on multidisciplinary project teams, and collaborate with colleagues to define and implement development strategies according to project timelines.
• Organize, evaluate, and present data in an effective and scientific manner.
• Ensure the local capability to rapidly leverage existing laboratory automation in order to reduce timelines that address design selection issues with drug development.
• Identify and recommend processes and technologies that achieve more efficient and cost effective data and knowledge management.
• Lead the definition and embedding of underpinning developability data standards for automation.
• Ensure compliance with all quality and data integrity regulations.
• Broad knowledge of analytical HPLC method development in support of pharmaceutical development focused in areas of developability and pre-formulation.
• Proficient in, and demonstrates, highly effective oral and written communication skills.
• Team player and ability to work in a matrix environment.
• Proven ability to troubleshoot and diagnosing problems in a variety of analytical instrumentation.
• Demonstrated ability to interface with multiple internal and external groups to successfully deliver scientific projects.
• Broad knowledge base and active member of the analytical or formulation community.
• High learning agility with the ability and desire to deal effectively with first-time situations or changing conditions.
• Knowledge and experience with statistical design of experiments and analysis of results.
• Knowledge of solid state analytical methods such as microscopy, Raman, XRD, etc.
• Demonstrated ability to integrate, test, and troubleshoot analytical instruments.
• Proven ability to translate scientific processes to new platforms and to identify new application areas.
Minimum BS in chemistry/engineering/pharmaceutics/biology or related scientific field.
Preferred MS in similar scientific disciplines.