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Transgenic Core Facility Jobs (NOW HIRING)

Generate stable transgenic lines, screen edited events, and contribute to invention disclosures ... Coordinate with the Nolan Lab single-cell team and Caltech core facilities as needed. Cross-cutting

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Transgenic Core Facility information

What are the key skills and qualifications needed to thrive as a Transgenic Core Facility specialist, and why are they important?

To excel in a Transgenic Core Facility, you need expertise in molecular biology, animal genetics, and experience with transgenic technologies, usually supported by an advanced degree in a life science field. Familiarity with laboratory instrumentation, gene editing tools like CRISPR/Cas9, and animal facility management systems is essential. Strong attention to detail, problem-solving abilities, and effective communication are important soft skills for collaborating with diverse research teams. These skills ensure the accurate generation and maintenance of genetically modified organisms critical for advancing biomedical research.

What does a typical day look like for someone working in a Transgenic Core Facility?

A typical day in a Transgenic Core Facility involves a balance of hands-on laboratory work and collaborative project management. Team members often perform microinjections, embryo transfers, and genotyping, while also maintaining meticulous records and ensuring compliance with ethical guidelines. Regular communication with researchers and principal investigators is essential to clarify project requirements and timelines, and troubleshooting technical issues is a common challenge. The work environment is highly collaborative, and professionals in this role often participate in ongoing training and contribute to process improvements.

What is a Transgenic Core Facility?

A Transgenic Core Facility is a specialized laboratory that provides services and expertise in the creation and analysis of genetically modified organisms, typically animals like mice or zebrafish. These facilities assist researchers by generating transgenic or knockout models, performing genetic modifications, and offering technical support for experimental design. Their work is essential for advancing biomedical research, as genetically engineered models help scientists study gene function, disease mechanisms, and potential therapies.

What is the difference between Transgenic Core Facility vs Transgenic Technician?

AspectTransgenic Core FacilityTransgenic Technician
CredentialsTypically requires advanced degrees (Master's or PhD) and specialized training in genetics and molecular biologyUsually requires a Bachelor's degree in biology or related field, with specialized training in transgenic techniques
Work EnvironmentResearch institutions, core facilities supporting multiple projects, collaborative settingLaboratories within research institutions, focused on executing transgenic procedures
Employer & Industry UsageUsed in academic, biotech, and pharmaceutical research settingsCommonly employed in research labs within similar industries

The Transgenic Core Facility oversees and manages transgenic projects, providing expertise and infrastructure, while the Transgenic Technician performs hands-on laboratory work to create and maintain transgenic models. Both roles are essential but differ in scope and responsibilities.

Infographic showing various Transgenic Core Facility job openings in the United States as of June 2026, with employment types broken down into 1% Locum Tenens, 3% As Needed, 95% Full Time, and 1% Temporary. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution.
Endowed Chair in Macular Degeneration Research

Endowed Chair in Macular Degeneration Research

UT Southwestern Medical Center

Dallas, TX • On-site

Full-time

Posted 25 days ago


UT Southwestern rating

7.8

Company rating: 7.8 out of 10

Based on 146 frontline employees who took The Breakroom Quiz

103rd of 870 rated healthcare providers


Job description

The UT Southwestern Department of Ophthalmology is offering a full-time faculty position for an established investigator conducting innovative research related to macular degeneration and other retinal degenerations.  Significant endowment support, programmatic development funds, and leadership opportunities are available for the qualified applicant.
As part of a major expansion in our vision research program, the Department is interested in recruiting a visionary expert in one or more of the following areas: (1) genetic, epigenetic and cellular mechanisms of macular/retinal degeneration, (2) retinal regeneration and Muller cell transdifferentiation, (2) neuro-inflammation and microglial biology, and (3) tissue engineering and in vitro modeling of macular disease.  We are particularly interested in applicants who can leverage their expertise to form strong collaborative relationships with other vision scientists and neuroscientists at UT Southwestern.
Candidates should possess a Ph.D. and/or M.D. degree, and they can be clinician-scientists or full-time scientists. Those who intend to engage in patient care must have or be eligible to obtain a Texas Medical License. Appointment and rank will be commensurate with academic accomplishments and experience. 
The successful candidate will find an extremely supportive environment within the Department of Ophthalmology, with a vibrant Retina Service to support translational and clinical projects. The candidate will also become a member of the renown UT Southwestern scientific community with national and international leaders in related fields within the O’Donnell Brain Institute, the Center for Alzheimer’s and Neurodegenerative Disease, and the Departments of Neuroscience, Neurology, Neurosurgery, Immunology, Biomedical Engineering, and others. They will enjoy access to state-of-art research core facilities, including imaging, histology, metabolic phenotyping, behavioral phenotyping, protein chemistry, structural biology, cryo-electron microscopy, genomics, genetics and transgenic technologies. A joint appointment in a basic science department is strongly encouraged.   
To apply, submit a CV and cover letter to the Endowed Chair in Macular Degeneration Search Committee at OphthalCareers@utsw.edu.
UT Southwestern is a top employer for health care  and is home to one of America’s leading medical schools and research institutions. The Department of Ophthalmology is a national leader in patient care, education, and vision research.  We also have one of the largest and most respected residency programs in the country. Check us out on Twitter (@UTSWOphth) and Instagram (@UTSWeye).
The Dallas-Fort Worth Metroplex isn’t just a great place to work, it’s one of the most exciting regions in the country to live, offering a compelling blend of cultural, recreational, sports, and entertainment activities all year long. Check out what your life would be like to work and live in Dallas! 
To learn more about the benefits UT Southwestern offers, visit: https://www.utsouthwestern.edu/employees/hr-resources/
Consideration may be given to applicants seeking less than a full-time schedule. Appointment rank will be commensurate with academic accomplishments and experience. 
This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.
UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community.  As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.


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