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Principal Scientist Pre Formulation Jobs (NOW HIRING)

Henkel AG & Co. KGaA

Principal Scientist

Darien, CT

Independently lead the formulation design, development, optimization, and scale-up of hair care and ... Mentor and provide technical guidance to junior scientists and support the development of team ...

Henkel

Principal Scientist

Darien, CT · On-site

$110K - $120K/yr

Independently lead the formulation design, development, optimization, and scale-up of hair care and ... Mentor and provide technical guidance to junior scientists and support the development of team ...

Henkel AG & Co. KGaA

Principal Scientist

Darien, CT

Independently lead the formulation design, development, optimization, and scale-up of hair care and ... Mentor and provide technical guidance to junior scientists and support the development of team ...

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Principal Scientist Pre Formulation information

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$68.5K

$144K

$190.5K

How much do principal scientist pre formulation jobs pay per year?

As of Jun 9, 2026, the average yearly pay for principal scientist pre formulation in the United States is $144,009.00, according to ZipRecruiter salary data. Most workers in this role earn between $117,500.00 and $169,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Principal Scientist in Pre Formulation, and why are they important?

To thrive as a Principal Scientist in Pre Formulation, you need an advanced degree (PhD or MS) in pharmaceutical sciences or a related field, with deep expertise in drug formulation, solid-state characterization, and preclinical development. Proficiency with analytical techniques (e.g., HPLC, DSC, XRPD), formulation development software, and regulatory documentation systems is commonly required. Strong leadership, problem-solving, and communication skills are essential for guiding teams and collaborating across functions. These qualifications ensure the successful design and optimization of drug formulations that meet safety, efficacy, and regulatory standards.

What is the difference between Principal Scientist Pre Formulation vs Principal Scientist Formulation?

AspectPrincipal Scientist Pre FormulationPrincipal Scientist Formulation
CredentialsAdvanced degree in pharmacy, chemistry, or related field; extensive industry experienceSimilar credentials; focus on formulation development expertise
Work EnvironmentEarly-stage drug development, laboratory research, formulation screeningLate-stage development, scale-up, manufacturing support
Industry UsageUsed in pharmaceutical R&D to optimize compound properties before formulationApplied during formulation development to create final drug products

While both roles require advanced scientific credentials and industry experience, the Principal Scientist Pre Formulation focuses on understanding and optimizing drug properties before formulation, whereas the Principal Scientist Formulation concentrates on developing and scaling final drug products for manufacturing.

What does a Principal Scientist Pre Formulation do?

A Principal Scientist Pre Formulation leads research and development efforts focused on the early stages of pharmaceutical product formulation. They are responsible for studying the physical and chemical properties of active pharmaceutical ingredients (APIs) to determine the most suitable forms and formulations for further development. This role involves designing experiments, analyzing data, collaborating with cross-functional teams, and guiding junior scientists to ensure that formulations are stable, effective, and manufacturable.

What are some common challenges faced by Principal Scientists in Pre-Formulation, and how can they be addressed?

Principal Scientists in Pre-Formulation often encounter challenges such as managing complex project timelines, addressing the variability of raw material properties, and ensuring robust data interpretation for formulation development. These challenges can be addressed by fostering close collaboration with analytical, process, and regulatory teams, implementing thorough risk assessment strategies, and maintaining up-to-date knowledge of emerging technologies. Building a strong cross-functional network and leveraging project management tools also help streamline communication and facilitate timely problem-solving.

Principal Scientist

Henkel AG & Co. KGaA

Darien, CT

Other

Posted 25 days ago

Job description

About this Position AtHenkel, you'll be part of an organization that's shaping the future throughinnovation, sustainability and collaboration. With our trusted brands likePersil, 'all, Loctite, Snuggle, and Schwarzkopf and our cutting-edgetechnologies, you'll have countless opportunities to explore new paths andgrow.
Thisposition is with our Consumer Brands business unit - where we empower ouremployees to bring the best Laundry & Home Care and Hair products to peoplearound the world.
Dare to learn new skills, advance in your career andmake an impact at Henkel.  What youll do 
  • Independently lead the formulation design, development, optimization, and scale-up of hair care and styling products from ideation through commercialization
  • Apply advanced technical expertise in surfactants, conditioning systems, polymers, emulsions, silicones, rheology modifiers, and active delivery systems to create innovative formulations
  • Identify and solve complex formulation, stability, compatibility, and manufacturing challenges
  • Translate consumer insights, market trends, and performance benchmarks into technically viable product solutions
  • Design and execute experimental plans, analyze data, and drive formulation decisions based on sound scientific principles
  • Lead technical assessment of competitive products and identify opportunities for innovation and differentiation
  • Partner closely with pilot plant and manufacturing teams to ensure smooth scale-up, process optimization, and robust commercialization
  • Collaborate cross-functionally with Marketing, Regulatory, Quality, Packaging, and Procurement to ensure products meet all performance, compliance, and cost requirements
  • Mentor and provide technical guidance to junior scientists and support the development of team capabilities
  • Develop products and work processes in accordance with Henkel SHE-Q Standards ensuring consumer safety and compliance with applicable regulations.
  • Follow established or create occupational workplace assessments, HAZOPs, and SOPs as needed to maintain a safe

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